|
KMID : 0377519840090030363
|
|
Chung-Ang Journal of Medicine
1984 Volume.9 No. 3 p.363 ~ p.370
|
|
|
Secretory Component in Chronic Cervicitis, Adenocarcinoma and Adenosquamous Cell Carcinoma of the Uterine Cervix
|
|
Lee Nam-Gyu
Bae Do-Hwan
|
|
|
Abstract
|
|
|
|
To observe correlation between morphological differentiation and secretory component in the carcinoma cells, immunohistochemical study was carried out with 10 cases of chronic cervicitis, 27 cases of adenocarcinoma and 10 cases of adenosquamous cell carcinoma of the uterine cervix. The results were as follows: 1. The columnar cells of uterine endocervix showed mild to moderate reaction of secretory component especially at the squamocolummar juntion and mild reactions in the stromal glandular epithelium. Mucin was negative. 2. The adenocarcinoma showed mild to moderate reaction of secretory component in the cell surface and cytoplasm of tubular type by 4 cases and 15 cases out of 19 cases. Intensity stain reaction in the adenocarcinoma increased more than chronic cervicitis. Tumor cells of papillary type and poorly differentiated cells were negative or weakly reactive. Mucin was negative. 3. In the adenosquamous cell carcinoma were seen similar reaction in respect to the pure type of adenocarcinoma. Squamous cell component was negative. 4. Therefore, secretory component was moderate to markedly stained in the well differentiated tubular adenocarcinoma cells more than in papillary of poorly differentiated cells. Close correlation between amount of secretory component and morphological differentiation of carcinoma cells was suggested.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|